What are mosaic embryos?
Mosaic embryos are those that are suspected to have both normal and abnormal cells, resulting in a mix of genetic material. In other words, some cells have the correct number of chromosomes, while others have an extra or missing chromosome. This can occur naturally during cell division or could be an artifact of the testing process.
What are the chances of success with mosaic embryos?
The success rates of transferring mosaic embryos can vary, depending on the specific genetic makeup of the embryo. Some mosaic embryos can result in a healthy pregnancy, while others may not implant or result in a miscarriage.
How are mosaic embryos identified?
Mosaic embryos are identified through a process called preimplantation genetic testing (PGT), which analyzes the genetic material of the embryo. This allows for the identification of any chromosomal abnormalities, including mosaicism. The transformation of technology in the past few decades has increased the resolution of our results, allowing us to see these more nuanced findings, which were previously undetectable using older technology.
What are the risks associated with transferring mosaic embryos?
The main risk associated with transferring mosaic embryos is the potential for a genetic abnormality or developmental issue in the resulting pregnancy. However, it’s important to note that the risks can vary and depend on the specific genetic makeup of the embryo.
What are the benefits of considering mosaic embryo transfer?
Mosaic embryo transfer can offer hope for those who may not have other embryos that are clearly euploid. It can also provide an opportunity to potentially increase the chances of a successful pregnancy.
What should I consider before transferring mosaic embryos?
Before deciding to transfer a mosaic embryo, you may benefit from speaking to a genetic counselor. As genetic counselors, we specialize in helping each patient make sense of the data, the specific risks that might be present for your embryo(s), your feelings about other testing options and fertility options that are on the table, and putting it all together to make a decision that feels right to you. There is no one-size-fits-all solution to making meaning of genetic risk, and the data is evolving quickly. And that is why we are here to help interpret and give you the specific information that can help you make decisions.
In conclusion, considering the transfer of mosaic embryos can be a complex decision. By understanding the basics of mosaic embryos, their identification, and the associated risks and benefits, you can make an informed decision that aligns with your values and goals. If you have a mosaic embryo and are interested in learning more about the potential outcomes and making a decision that feels right to you, schedule a time to speak with us.\
Disclaimer: Please keep in mind that the information provided here is not meant to be a medical opinion about your specific case. The problems of every patient are unique and should be addressed by their physician or other healthcare professionals in an individual conversation. You are welcome to bring up questions inspired by this blog post with your medical team. However, no one should use this blog as a source of medical care.