Social Media Links

More Mosaic Embryo Data

Big news in this study! Will make so many patients reconsider their mosaic embryos.
“An elaboration of the results of this trial show that excluding putative mosaic embryos (either with low or moderate degree of mosaicism) drastically reduces cumulative pregnancy rate per cycle started (up to −34%) without improving any clinical outcome measure associated with patient’s safety (e.g., miscarriage, chromosomally abnormal conception).”
But we're not sure about the authors' thoughts on moving away from invasive prenatal testing. . . Seems a bit early for the data we've got so far. Talk to one of our genetic counselors for help with decision-making if you are thinking about transferring a mosaic embryo.  

Talking to Children About Embryo Donation

Overlap alert: this is Gina's collaborative project with Maya Grobel of One More Shot and Jen Vesbit of Embryo Donation Support! Worth a watch to anyone considering third party reproduction, including egg and sperm donation.

In this live webinar, the EM•POWER team explores different ways to talk with children about embryo donation. We share tools and tips from our family experiences and discuss ways to support children as they shape their own unique narratives.

Normalizing Family Diversity and Known Gamete Donation

Representation matters! Shout out to Bless This Mess creators for featuring diverse family forms in authentic character development! Nicole Richie has a cameo in this show and her character and her back-story is simply adorable.

Normalizing life in a diverse family structure is so needed, so that these conversations can move past educating the world about conception stories. Embracing genetic identity no matter how a family comes together. . . we'll get there!

Expanded Carrier Screening and the Complexity of Implementation

Great article by the prenatal genetics team at UCSF! Fertility patients often like the reassurance that comes from a big carrier screening platform before they pursue treatment. And most of the time, it is reassuring. When it's not and when you have questions, consider working with a genetic counselor. Expanded carrier screening using NGS (next-generation sequencing) is a double-edged sword. It gives us better sensitivity, absolutely . . . but it can also leave us in a pickle when it comes to interpreting rare variants. From the article: 'Although the American College of Obstetricians and Gynecologists puts forth detailed guidance for deciding which diseases should be included on expanded carrier screening panels, a myriad of challenges arise when analyzing sequencing data that may call into question whether results consistently provide “meaningful information.”'

30 Years Since the Human Genome Project Began, What’s Next?

What we're reading and thinking about these days. Truly, the speed of innovation in genetics has been staggering. Every day we face new challenges in interpreting ALL THAT DATA. We are at an interesting crossroads in history where we have so much data, and are sometimes just scraping the surface of what we know about it clinically. If you or your patient has a genetic result that has you scratching your head, remember that genetic counselors are here to help!